Mellieħa holds centuries-old spiritual significance. The Sanctuary of Our Lady of Mellieħa, dedicated to the Virgin Mary, is a prominent spiritual landmark and dates back to the time that St. Paul got shipwrecked in Malta.

Mellieħa's spiritual history extends to prehistoric times with megalithic temples whose remains can still be seen around the rugged coast.

The town's natural beauty, from serene coastlines to rugged countryside, offers a serene backdrop for spiritual reflection, attracting seekers from various backgrounds. Mellieħa's profound spiritual roots, intertwined with its history and geography, continue to inspire those in search of a deeper connection with the sacred.